AB Sciex API 3000 ™ LC/MS/MS triple quadrupole tandem mass spectrometer

AB Sciex API 3000 ™ Introduction to LC/MS/MS liquid chromatography-mass spectrometry:

API 3000 ™ LC/MS/MS systems are suitable instruments for small molecule high-throughput quantitative analysis laboratories in application areas where their performance meets regulatory requirements.

This instrument can be applied to all quantitative analysis fields such as environmental analysis, food analysis, clinical research, and drug research, with good data stability and reproducibility; Industry API 5000 ™ And API 4000 ™ Like the system, API 3000 ™ It can also provide high-quality analytical data.

System Features

High sensitivity - New ion optics and vacuum technologies enable low detection and quantification limits for compound detection.

● Tandem Mass Spectrometry Performance - LINAC technology eliminates the "memory effect" problem of traditional tandem mass spectrometers and has fast scanning speed.

● Quickly establish analysis methods to achieve high-throughput analysis - automatically optimize ion source parameters and mass spectrometer parameters, establish analysis methods quickly, and analyze hundreds of samples per day.

Good durability and stability - The standard design of the mass spectrometry industry: ion source and interface technology provide stability. LINAC technology ensures the performance of MS/MS linear acceleration (LINAC). The high-pressure collision chamber technology improves the sensitivity of all MS/MS methods, increases the transmission efficiency of ions to the detector, and improves the performance of tandem mass spectrometry.

● Increase the stability of results - LINAC technology can prevent memory effects in MRM experiments.

One analysis can quantify more compounds - LINAC technology allows for reducing measurement residence time without compromising sensitivity in MRM experiments.

● Improved ionization technology - TurboIonSpray and APCI technology maintain stable performance over a wide range of mobile phase flow rates and compositions, with a large ion receiving surface (Sweet spot)

Simultaneous acquisition of MS and MS/MS data - Manufacturing stable hardware and Analyst software enables the "hybrid scanning method" (linking various scanning methods together) to obtain information in one injection.

Main parameters

● Configure TurbolonSpray and APCI ion sources

The flow rate ranges are 2-1000ul/min and 0.2-2.0ml/min, respectively

● Transport rate of collision focused fourth level rod ions

Linear acceleration collision LINAC technology can eliminate memory effects and improve sensitivity detection system

The pulse counting detector can quickly switch between positive/negative ion detection modes

Dynamic range: 1-4E6cps vacuum system

Two stage turbo molecular pump, air-cooled, maintenance free

Automatically shut down the system data processing and control system after power failure

● Quickly perform alternating MS and CID/MS scans

● Can automatically perform real-time data and post-processing UV input and LC control

Can control 9 types of LC pumps from different manufacturers, including injection pumps and automatic samplers

● Can control detectors such as UV, fluorescence, and ECD to collect data simultaneously with a mass spectrometer